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  1. Now find which GT are hom in both of the second two (parents) but het in the first (child):

    Code Block
    join NA12892.raw.vcf.simple.hom NA12891.raw.vcf.simple.hom > both.hom
    join both.hom NA12878.raw.vcf.simple.het | wc -l
    

 

Virmid - an advanced auto-screener

 

GATK also has a host of VCF related screeners/joiners/overlapers etc.