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Code Block
cds
cp -r $BI/ngs_course/listeria_RNA_seq/data listeria_RNA_seq

If you want to skip the read alignment step...

To get right to the new stuff you can copy the mapped read BAM files and the reference sequence files that you will need from here:

Code Block

cds
cp -r $BI/ngs_course/listeria_RNA_seq/mapped_data listeria_RNA_seq

Then skip the mapping steps below.

File Name

Description

Sample

SRR034450.fastq

Single-end Illumina 36-bp reads

wild-type, biological replicate 1

SRR034451.fastq

Single-end Illumina 36-bp reads

ΔsigB mutant, biological replicate 1

SRR034452.fastq

Single-end Illumina 36-bp reads

wild-type, biological replicate 2

SRR034453.fastq

Single-end Illumina 36-bp reads

ΔsigB mutant, biological replicate 2

NC_017544.1.fasta

Reference Genome sequence (FASTA)

Listeria monocytogenes strain 10403S

NC_017544.1.gff

Reference Genome features (GFF)

Listeria monocytogenes strain 10403S

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  • Oliver, H.F., et al. (2009) Deep RNA sequencing of L. monocytogenes reveals overlapping and extensive stationary phase and sigma B-dependent transcriptomes, including multiple highly transcribed noncoding RNAs. BMC Genomics 10:641. Pubmed

You can view the data in the ENA SRA here: http://www.ebi.ac.uk/ena/data/view/SRP001753the ENA SRA here: http://www.ebi.ac.uk/ena/data/view/SRP001753

If you want to skip the read alignment step...

To get right to the new stuff, you can copy the mapped read BAM files and the reference sequence files that you will need from here:

Code Block

cds
cp -r $BI/ngs_course/listeria_RNA_seq/mapped_data listeria_RNA_seq

Then, skip the mapping and SAM/BAM conversion, sorting, indexing steps below.

Installing Bioconductor modules for R

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