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This code will perform a remote BLASTn against the RefSeq genome database, limited to human results without "clone" in the description.

Code Block
languagepy
from Bio.Blast import NCBIWWW

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blast_handle = NCBIWWW.qblast("blastn", "refseq_genomic", input_sequence, entrez_query="homo sapiens[orgn] NOT clone[all]")