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Genome Assembly (SPAdes) -- GVA2022

Genome Assembly (SPAdes) -- GVA2022

Overview

SPAdes is a De Bruijn graph assembler which has become the preferred assembler in numerous labs and workflows. In this tutorial we will use SPAdes to assemble an E. coli genome from simulated Illumina reads. Genome assembly is quite difficult (though as Oxford Nanopore lowers its error rate and tools using both its long reads and